Liposuction can be considered a preferable alternative to conventional surgery in pediatric lipomas that are bigger than 4 cm. Liposuction of pediatric lipomas has not been found in the English-language literature. The case of a 5-year-old girl who had liposuction of a large lipoma extending from the lower cervical to the right lumbar region is reported with a review of the literature on the technique, follow-up, and outcome of the procedure. Copyright 2002, Elsevier Science (USA). All rights reserved.