KLIMIK JOURNAL, vol.18, no.3, pp.103-109, 2005 (ESCI)
All adult patients undergoing cardiac surgery with sternotomy between January 14, 2002, and July 1, 2002 and who survived at least 4 days after surgery were included in the study. Potential risk factors and infection data were collected prospectively and analyzed by multivariate logistic regression analysis. Operating theatre type (newer ones were equipped with laminar flow ventilation system and with automatic doors which were always closed between entrances and exits; older ones were equipped with plenum ventilation system and with destroyed automatic doors which were kept generally open) were also included in the study as a risk factor. Potential risk factor data were complete for 991patients. There was 92 (9.3%) nosocomial infections in 72 (7.3%) patients. Sternal surgical site infections were the most frequently encountered infections (4.1%). Device-associated infection rates in per 1000 device utilization days were 12.5, 2.25 and 1.2 for ventilator-associated pneumoniae, central line-associated blood stream infections and urinary catheter-associated symptomatic urinary tract infections, respectively. Diabetes mellitus, preoperative transfusion, being operated in the older operating theatres, procedure exceeding 5 hours and mechanical ventilation longer than 24 hours were identified as independent risk factors for nosocomial infections following cardiac surgery.