A confirmatory report for the close interaction of Helicobacter pylori with gastric epithelial MUC5AC expression


Kocer B., Ulas M., Ustundag Y., Erdogan S., Karabeyoglu M., Yildirim O., ...More

JOURNAL OF CLINICAL GASTROENTEROLOGY, vol.38, no.6, pp.496-502, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1097/01.mcg.0000123168.86324.1b
  • Journal Name: JOURNAL OF CLINICAL GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.496-502
  • Keywords: Helicobacter pylori, gastric mucin, MUC 1, MUC2, MUC5AC, MUCIN GENE-EXPRESSION, CHROMOSOMAL LOCALIZATION, CLONING
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: Helicobacter pylori (H. pylori) infection is associated with the development of gastritis and peptic ulcer and is presumed to be a risk factor for low-grade B-cell lymphoma and gastric cancer. H. pylori also causes critical alterations in gastric mucin structure. Our aim was to determine the effect of H. pylori on MUC1, MUC2, and MUC5AC expression.