N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids

HÜR D., Dal S. F. E., Varol G. A., HÜR E.

JOURNAL OF ORGANOMETALLIC CHEMISTRY, cilt.696, sa.13, ss.2543-2548, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 696 Sayı: 13
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.jorganchem.2011.03.037
  • Dergi Adı: JOURNAL OF ORGANOMETALLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2543-2548
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation. (C) 2011 Elsevier B.V. All rights reserved.