N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids

HÜR D., Dal S. F. E., Varol G. A., HÜR E.

JOURNAL OF ORGANOMETALLIC CHEMISTRY, vol.696, no.13, pp.2543-2548, 2011 (SCI-Expanded) identifier identifier


In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation. (C) 2011 Elsevier B.V. All rights reserved.