Synthesis and antimicrobial activity of some thiazolyl-pyrazoline derivatives

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Atıf İçin Kopyala

Kaplancikli Z. A., Turan-Zitouni G., Ozdemir A., Revial G., Guven K.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.182, sa.4, ss.749-764, 2007 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 182 Sayı: 4
• Basım Tarihi: 2007
• Doi Numarası: 10.1080/10426500601047529
• Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.749-764
• Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Some 1-(4-aryl-2-thiazolyl)-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives (TP 1-28) were synthesized by reacting substituted 3-(2-thienyl)-5-aryl-1-thiocarbamoyl-2-pyrazolines (P 1-7) with phenacyl bromides in ethanol. Structures of the synthesized compounds were confirmed by elemental analyses and IR, H-1-NMR and MS-FAB(+) spectral data. Their antimicrobial activities against Escherichia coli (NRRL B-3704), Staphylococcus aureus (NRLL B-767), Salmonella typhimurium (NRRL B-4420), Bacillus cereus (NRRL B-3711), Listeria monocytogenes (Ankara University, Faculty of Veterinary, Ankara, Turkey), Aeromonas hydrophila (Ankara University, Faculty of Veterinary Ankara, Turkey), Candida albicans, and Candida glabrata (isolates obtained from Osmangazi University, Faculty of Medicine, Eskisehir Turkey) were investigated. A significant level of activity was illustrated.