Collagenases in gingival crevicular fluid in type 1 diabetes mellitus

Safkan-Seppala B., Sorsa T., Tervahartiala T., Beklen A., Konttinen Y. T.

JOURNAL OF PERIODONTOLOGY, vol.77, no.2, pp.189-194, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1902/jop.2006.040322
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.189-194
  • Eskisehir Osmangazi University Affiliated: Yes


Background: Studies have demonstrated that high levels of collagenase activity in gingival crevicular fluid (GCF) are associated with degradation of periodontal tissues in progressive periodontitis compared to periodontally healthy tissues. Because the activation of collagenases is an important issue in periodontitis, we have studied the activation of collagenase in gingival crevicular fluid samples of diabetic patients.