A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone

Wu S., Cohen R., Simsek E., Senses D., Yar N., Grasberger H., ...More

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol.91, no.5, pp.1887-1895, 2006 (SCI-Expanded) identifier identifier identifier


Context: Resistance to thyroid hormone ( RTH) is a dominantly inherited syndrome of variable tissue hyporesponsiveness to thyroid hormone ( TH).