The impact of melatonin on glucose homeostasis

YEGİN Z. A. , Mutluay R. , Elbeg Ş., KARAKUŞ R., Çakir N.

Turkish Journal of Endocrinology and Metabolism, cilt.13, sa.3, ss.52-55, 2009 (SCI Expanded İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Konu: 3
  • Basım Tarihi: 2009
  • Dergi Adı: Turkish Journal of Endocrinology and Metabolism
  • Sayfa Sayıları: ss.52-55


Objective: Melatonin is a pineal product mainly charged with the maintenance of antioxidant conditions in human. This study is performed to identify the short-term effect of melatonin on glucose homeostasis in diabetic patients. Materials and Methods: Melatonin and placebo were given perorally to sixty patients. Blood glucose and insulin levels were measured with constant intervals. Results: No significant correlation was found among the levels of glucose, insulin and HOMA-IR index at any time after melatonin/placebo administration. Conclusions: Prospective studies with long-term use of melatonin are needed to define the exact role of melatonin in glucose homeostasis.