The impact of melatonin on glucose homeostasis


YEGİN Z. A. , Mutluay R., Elbeg Ş., KARAKUŞ R., Çakir N.

Turkish Journal of Endocrinology and Metabolism, vol.13, no.3, pp.52-55, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 3
  • Publication Date: 2009
  • Journal Name: Turkish Journal of Endocrinology and Metabolism
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.52-55
  • Eskisehir Osmangazi University Affiliated: No

Abstract

Objective: Melatonin is a pineal product mainly charged with the maintenance of antioxidant conditions in human. This study is performed to identify the short-term effect of melatonin on glucose homeostasis in diabetic patients. Materials and Methods: Melatonin and placebo were given perorally to sixty patients. Blood glucose and insulin levels were measured with constant intervals. Results: No significant correlation was found among the levels of glucose, insulin and HOMA-IR index at any time after melatonin/placebo administration. Conclusions: Prospective studies with long-term use of melatonin are needed to define the exact role of melatonin in glucose homeostasis.