Bactericidal effects of commonly used antiseptics/disinfectans against nosocomial pathogens and relationship between antibacterial and biocide resistance Yaygin kullanilan anti̇septi̇k/dezenfektanlarin nozokomi̇yal bakteri̇yel patojenler üzeri̇ndeki̇ etki̇nli̇kleri̇ ve anti̇bakteri̇yel ve bi̇yosi̇t di̇renç i̇li̇şki̇si̇

Fiçici S. E., Durmaz G., İLHAN S., Akgun Y., Köşgeroǧlu N.

Mikrobiyoloji Bulteni, cilt.36, ss.259-269, 2002 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36
  • Basım Tarihi: 2002
  • Dergi Adı: Mikrobiyoloji Bulteni
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.259-269
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Bactericidal efficacy of seven different disinfectants (chlorhexidine gluconate, povidone-iodine, glutaraldehyde, benzalkonium chloride, sodium hypochloride, ethoxydiamino acridine, the mixture of "12% ethandiol + 0.5% pentanediol + 7.5% didecyldimethylammonium cloride") commonly used at Osmangazi University, Medical Faculty Hospital, was investigated against frequent nosocomial bacterial pathogens (19 Gram-negative and 25 Gram-positive strains) by using modified Kelsey-Sykes method. Chlorhexidine gluconate, povidone-iodine and glutaraldehyde were determined as the most effective disinfectants against all of the pathogens. There was no significant difference in terms of biocide resistance between antibiotic sensitive and resistant strains. All of the P. aeruginosa strains were found to be resistant to 0.01% benzalkonium chloride and 0.25%, 0.5% and 1% concentrations of "12% ethandiol + 0.5% pentanediol + 7.5% didecyldimethyl ammonium cloride" mixture. One vancomycin resistant E. faecium strain and one extended spectrum beta-lactamase (ESBL) positive K.pneumoniae strain were found to be resistant to 0.55% sodium hypochloride. Ethoxydiamino acridine showed little or no activity against all tested strains.