The Potential Role of Peritumoral Apparent Diffusion Coefficient Evaluation in Differentiating Glioblastoma and Solitary Metastatic Lesions of the Brain.

Tepe M., Saylisoy S., Toprak U., Inan I.

Current medical imaging, vol.17, no.10, pp.1200-1208, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 10
  • Publication Date: 2021
  • Doi Number: 10.2174/1573405617666210316120314
  • Journal Name: Current medical imaging
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.1200-1208
  • Keywords: Glioblastoma, brain metastasis, apparent diffusion coefficient (ADC), peritumoral edema, GBM, diffusion MM, MAGNETIC-RESONANCE-SPECTROSCOPY, HIGH-GRADE GLIOMAS, DIAGNOSTIC-VALUE, VASOGENIC EDEMA, MULTIFORME, VALUES, TUMORS, AID
  • Eskisehir Osmangazi University Affiliated: Yes


Objective: Differentiating glioblastoma (GBM) and solitary metastasis is not always possible using conventional magnetic resonance imaging (MRI) techniques. In conventional brain MRI, GBM and brain metastases are lesions with mostly similar imaging findings. In this study, we investigated whether apparent diffusion coefficient (ADC) ratios, ADC gradients, and minimum ADC values in the peritumoral edema tissue can be used to discriminate between these two tumom.