Toll-like receptors 2 and 5 in human gingival epithelial cells co-operate with T-cell cytokine interleukin-17


Beklen A. , Sorsa T., Konttinen Y. T.

ORAL MICROBIOLOGY AND IMMUNOLOGY, cilt.24, sa.1, ss.38-42, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Konu: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1399-302x.2008.00473.x
  • Dergi Adı: ORAL MICROBIOLOGY AND IMMUNOLOGY
  • Sayfa Sayıları: ss.38-42

Özet

Periodontitis begins as the result of perturbation of the gingival epithelial cells caused by subgingival bacteria interacting with the epithelial cells via pattern recognition receptors. Toll-like receptors (TLRs) have been shown to play an important role in the recognition of periodontal pathogens so we have studied the interaction of TLR ligands with TLR2 and TLR5 for cytokine production in the cultures of gingival epithelial cells.