Levocetirizine Dihydrochloride-Loaded Chitosan Nanoparticles: Formulation and In Vitro Evaluation

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Yurtdas Kirimlioglu G., Ozturk A. A.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.17, sa.1, ss.27-35, 2020 (ESCI, Scopus, TRDizin)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17 Sayı: 1
• Basım Tarihi: 2020
• Doi Numarası: 10.4274/tjps.galenos.2018.34392
• Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.27-35
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objectives: The aim of the present study was to formulate levocetirizine hydrochloride (LCD)-loaded chitosan nanoparticles at submicron level with high entrapment efficiency and prolonged effect for optimizing the plasma drug concentration enhancing bioavailability.