Synthesis and antimicrobial activity of some 2-(benzo[d]oxazol/benzo[d]imidazol-2-ylthio)-N-(9H-fluoren-9-yl)acetamide derivatives

Turan-Zitouni, Gulhan; Kaplancikli, Zafer; Ozdemir, Ahmet; Revial, Gilbert; Guven, Kiymet

doi:10.1080/10426500601047016

Synthesis and antimicrobial activity of some 2-(benzo[d]oxazol/benzo[d]imidazol-2-ylthio)-N-(9H-fluoren-9-yl)acetamide derivatives

Atıf İçin Kopyala

Turan-Zitouni G., Kaplancikli Z. A., Ozdemir A., Revial G., Guven K.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.182, sa.3, ss.639-646, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 182 Sayı: 3
Basım Tarihi: 2007
Doi Numarası: 10.1080/10426500601047016
Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.639-646
Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Some 2-(benzo[d]oxazol/benzo[d]imidazol-2-ylthio)-N-(9H-fluoren-9-yl)acetamide derivatives were synthesized by reacting 9-(chloroacetylamino)fluorene with benzo[d]oxazol/benzo[d]imidazol-2-thiole in acetone in the presence of K2CO3. Chemical structures of the compounds were elucidated by H-1 NMR spectroscopy and FAB(+) mass spectrometty. Their antimicrobial activities against Micrococcus luteus (NRLL B-4375), Bacillus cereus (NRRL B-3711), Proteus vulgaris (NRRL B-123), Salmonella typhimurium (NRRL B-4420), Staphylococcus aureus (NRRL B-767), Escherichia coli (NRRL B-3704), Candida albicans, and Candida glabrata were investigated, and significant activity was observed.