The antifungal activity and biotransformation of diisophorone by the fungus Aspergillus niger
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, cilt.79, sa.12, ss.1366-1370, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 79 Sayı: 12
- Basım Tarihi: 2004
- Doi Numarası: 10.1002/jctb.1130
- Dergi Adı: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1366-1370
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
The microbial transformation of racemic diisophorone was investigated using the plant pathogen Aspergillus niger as a biocatalyst. Incubation of diisophorone with Aspergillus niger gave 8alpha-hydroxydiisophorone, 10-hydroxydiisophorone and 17-hydroxydiisophorone on the basis of their spectroscopic data including two-dimensional NMR analysis, nOe and an X-ray crystallographic study. The antifungal activity of diisophorone against Aspergillus niger was also examined. (C) 2004 Society of Chemical Industry