A Case Report and Pediatric Literature Review: Povidone as a Rare Cause of Anaphylaxis in Children


Baysal S., ANIL H., HARMANCI K.

Pediatric, Allergy, Immunology, and Pulmonology, cilt.37, sa.2, ss.56-59, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1089/ped.2024.0036
  • Dergi Adı: Pediatric, Allergy, Immunology, and Pulmonology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.56-59
  • Anahtar Kelimeler: anaphylaxis, children, pediatric allergy, polyvinylpyrrolidone, povidone, povidone anaphylaxis
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Povidone, a synthetic polymer commonly used in various products such as antiseptics, cosmetics, and medications, has been associated with allergic reactions, including anaphylaxis. Despite its widespread use, cases of povidone-induced anaphylaxis, especially in children, are under-recognized. This case report aims to highlight the importance of considering povidone allergy in pediatric patients presenting with anaphylaxis. Case Presentation: We describe a 3-year-old boy who experienced anaphylaxis following the application of povidone-iodine antiseptic solution to a leg wound. He presented with generalized urticaria, angioedema, dyspnea, and cough. Prompt diagnosis and management were initiated in the emergency department. He experienced the second anaphylaxis with povidone-containing eye drops prescribed during an ophthalmology visit. Conclusions: Povidone allergy should be considered in pediatric patients presenting with anaphylaxis, especially those with idiopathic reactions or multiple drug allergies. Clinicians should emphasize patient education on label reading and the provision of adrenaline autoinjectors to prevent life-threatening reactions associated with povidone exposure.