Increased carotid artery intima-media thickness in patients with tympanosclerosis: Common risk factors with atherosclerosis?

Doluoglu S., Gocer C., Toprak U., Iriz A., Uyar M., Eryilmaz A.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, vol.31, pp.199-202, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31
  • Publication Date: 2015
  • Doi Number: 10.1016/j.kjms.2015.01.003
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.199-202
  • Keywords: Atherosclerosis, Carotid artery, Tympanosclerosis, MIDDLE-EAR EFFUSIONS, C-REACTIVE PROTEIN, HOMOCYSTEINE, INSERTION
  • Eskisehir Osmangazi University Affiliated: No


We investigated the relationship between tympanosclerosis, known atherosclerotic risk factors, and the intima-media thickness of bilateral carotid arteries using ultrasonography. A total of 122 patients admitted to our clinic with chronic otitis media between 2005 and 2010 were included in the study. The study group consisted of 61 patients with tympanosclerosis; the control group comprised 61 patients without tympanosclerosis. Internal carotid artery intima-media thickness (CAIMT), total cholesterol, triglyceride, low- and high-density lipoprotein cholesterol, C-reactive protein, and homocysteine levels were measured in all patients. Homocysteine, low-density lipoprotein, total cholesterol, and triglyceride levels in the study group were higher compared with those of the control group (p < 0.05). Right and left CAIMT was greater in the study group versus the control group (p <= 0.001). In conclusion, atherosclerosis and tympanosclerosis were associated with identical risk factors; in the tympanosclerosis group, CAIMT was increased significantly. Copyright (C) 2015, Kaohsiung Medical University. Published by Elsevier Taiwan LLC. All rights reserved.