Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

TAY, NAİME; YURTTAŞ, LEYLA; DEMİRAYAK, ŞEREF

doi:10.3109/14756366.2011.599030

Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

TAY N. F., YURTTAŞ L., DEMİRAYAK Ş.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, cilt.27, sa.4, ss.515-520, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 4
Basım Tarihi: 2012
Doi Numarası: 10.3109/14756366.2011.599030
Dergi Adı: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.515-520
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

In this study, some N-[4-(Benzothiazole-2-yl)phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. The anticancer activities of the compounds obtained were investigated. It was observed that some of the compounds, namely 25 and 38, showed notable anticancer activity.