Preconditioning-like amelioration of erythropoietin against laparoscopy-induced oxidative injury


Ates E., Yilmaz S., Ihtiyar E., Yasar B., Karahuseyinoglu E.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, vol.20, no.5, pp.815-819, 2006 (SCI-Expanded) identifier identifier identifier

Abstract

Background; Laparoscopic surgery has gained wide acceptance for almost every kind of surgical procedure, although it has produced significant oxidative injury to intraabdominal organs depending on the pressure level and the kind of the gas used. The literature describes several preventive measures for decreasing the postlaparoscopic oxidative injury such as low intraabdominal pressure, gasless laparoscopy, and laparoscopic preconditioning. Erythropoietin was shown previously to decrease ischemia-reperfusion injury to the liver. The current study evaluated the effect of erythropoietin against laparoscopy-induced oxidative injury, as compared with laparoscopic preconditioning.