Evaluation of Pleiotropic Effects of Statins in Chronic Renal Failure Patients

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ÖZKURT S., SOYDAN M., ŞAHİN G., BAL C., Alatas O.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.20, no.2, pp.150-155, 2011 (ESCI, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 20 Issue: 2
• Publication Date: 2011
• Doi Number: 10.5262/tndt.2011.1002.06
• Journal Name: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.150-155
• Open Archive Collection: AVESIS Open Access Collection
• Eskisehir Osmangazi University Affiliated: Yes

Abstract

OBJECTIVES : Atherosclerosis is seen more frequently in patients with chronic renal failure (CRF) due to the oxidative stress, chronic inflammation and endothelial dysfunction. Besides lowering total and low density lipoprotein (LDL) cholesterol levels, statins also lower the frequency of cardiovascular incidents in patients with chronic renal failure by their pleiotropic effects. We aimed to investigate whether atorvastatin had pleiotropic effects in dialysis patients.