European Heart Rhythm Association (EHRA) position paper on arrhythmia management and device therapies in endocrine disorders, endorsed by Asia Pacific Heart Rhythm Society (APHRS) and Latin American Heart Rhythm Society (LAHRS)

Creative Commons License

GÖRENEK B., Boriani G., Dan G., Fauchier L., Fenelon G., Huang H., ...More

EUROPACE, vol.20, no.6, pp.895-924, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1093/europace/euy051
  • Journal Name: EUROPACE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.895-924
  • Keywords: Endocrine disorders, Arrhythmias, Atrial fibrillation, Ventricular arrhythmias, Cardiac implantable electronic device, Pacemaker, Implantable cardioverter-defibrillator, Catheter ablation, Diabetes, Thyroid disorders, Hyperthyroidism, Hypothyroidism, Pheochromocytoma, Growth hormone dysfunction, Hyperaldosteronism, Adrenal insufficiency, Parathyroid disease, Stroke, Oral anticoagulation, EHRA position paper, TYPE-2 DIABETES-MELLITUS, SUDDEN CARDIAC DEATH, LONG-QT SYNDROME, IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS, POSTOPERATIVE ATRIAL-FIBRILLATION, AMIODARONE-INDUCED THYROTOXICOSIS, LIFE-THREATENING ARRHYTHMIA, INDUCED THYROID-DYSFUNCTION, SICK SINUS SYNDROME, IN-BED SYNDROME
  • Eskisehir Osmangazi University Affiliated: Yes


Endocrine disorders are associated with various tachyarrhythmias, including atrial fibrillation (AF), ventricular tachycardia (VT), ventricular fibrillation (VF), and bradyarrhythmias. Along with underlying arrhythmia substrate, electrolyte disturbances, glucose, and hormone levels, accompanying endocrine disorders contribute to development of arrhythmia. Arrhythmias may be life-threatening, facilitate cardiogenic shock development and increase mortality. The knowledge on the incidence of tachy-and bradyarrhythmias, clinical and prognostic significance as well as their management is limited; it is represented in observational studies and mostly in case reports on management of challenging cases. It should be also emphasized, that the topic is not covered in detail in current guidelines. Therefore, cardiologists and multidisciplinary teams participating in care of such patients do need the evidence-based, or in case of limited evidence expert-opinion based recommendations, how to treat arrhythmias using contemporary approaches, prevent their complications and recurrence in patients with endocrine disorders. In recognizing this close relationship between endocrine disorders and arrhythmias, the European Heart Rhythm Association (EHRA) convened a Task Force, with representation from Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE), with the remit of comprehensively reviewing the available evidence and publishing a joint consensus document on endocrine disorders and cardiac arrhythmias, and providing up-to-date consensus recommendations for use in clinical practice.