ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.17, sa.1, ss.8-17, 2017 (SCI-Expanded)
Objective: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary hypertension (PH) model in rats. In particular, the inter-relationships between PH and matrix metalloproteinases (MMPs) were investigated.