EVALUATION OF IL-1 beta GENE POLYMORPHISM IN THE PATIENTS WITH RECURRENT PREGNANCY LOSS
NOBEL MEDICUS, cilt.6, sa.1, ss.34-38, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 1
- Basım Tarihi: 2010
- Dergi Adı: NOBEL MEDICUS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.34-38
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Objective: In the recent studies it is suggested that problems in immunologic and inflammatory processes have an affect on pregnancy losses in women suffering from recurrent abortions. Pro-inflammatory cytokines were also reported to play roles in the pathogenesis of the idiopathic recurrent abortions. Interleukin 1 beta (IL-1 beta) which is generated by monocytes, macrophages and epithelial cells, is an important pro-inflammatory cytokine. In this study whether the polymorphisms of exon 5 of IL-1 beta gene were related to recurrent pregnancy losses was examined.