The (Hea)[B(ph)(2)(2,3-pydc)] (1) and (Hea)[B(ph)(2)(2,5-pydc)] (2) boron compounds (2,3-H(2)pydc = 2,3-pyridinedicarboxylic acid, 2,5-H(2)pydc = 2,5-pyridinedicarboxylic acid, Hea = ethanolammonium) were synthesized and characterized by elemental analysis, spectroscopic measurements (UV-Vis, B-11 NMR, C-13 NMR, H-1 NMR and IR spectra) and single crystal X-ray diffraction technique. Compound 1 and 2 crystallize in the monoclinic space group P2(1)/c. The crystal packing of compound 1 is stabilized through strong intermolecular hydrogen bonding and C-H center dot center dot center dot pi interactions, resulting in a 3D framework. The individual molecules of 2 are connected by the N-H center dot center dot center dot O and O-H center dot center dot center dot O hydrogen bonds leading to two-dimensional hydrogen bonded layer. The in vitro antibacterial and anticandidal activities of (1) and (2) were evaluated by disc diffusion method and MIC tests. Both new complexes showed antimicrobial activity against MRSA and clinical and standard yeast isolates. (C) 2011 Elsevier B. V. All rights reserved.