The effects of bupivacaine injection and oral nitric oxide on extraocular muscle in the rabbit

Bilgin B., Gursoy H. H., Basmak H., Ozkurt M., Tuncel N., CANAZ F., ...More

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol.251, no.9, pp.2227-2233, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 251 Issue: 9
  • Publication Date: 2013
  • Doi Number: 10.1007/s00417-013-2390-8
  • Journal Name: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2227-2233
  • Keywords: Bupivacaine, Nitric oxide, Extraocular muscle, Rabbit, ISOSORBIDE DINITRATE, STRENGTH, REGENERATION, ACTIVATION, REPAIR
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Nitric oxide (NO) plays a key role in muscle regeneration, which is the primary response, observed during bupivacaine-induced extraocular muscle (EOM) hypertrophy. Our aims were to investigate the effects of bupivacaine injection into the rabbit EOM and the interaction with NO.