Comparison of Effects of Separate and Combined Sugammadex and Lipid Emulsion Administration on Hemodynamic Parameters and Survival in a Rat Model of Verapamil Toxicity

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Tulgar S., Kose H. C., Piroglu I. D., Karakilic E., Ates N. G., Demir A., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.22, ss.984-990, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2016
  • Doi Numarası: 10.12659/msm.896125
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.984-990
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background: Toxicity of calcium channel blockers leads to high patient mortality and there is no effective antidote. The benefit of using 20% lipid emulsion and sugammadex has been reported. The present study measured the effect of sugammadex and 20% lipid emulsion on hemodynamics and survival in a rat model of verapamil toxicity.