Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis

Beklen, ARZU; Hukkanen, M.; Richardson, R.; Konttinen, Y.

doi:10.1111/j.1399-302x.2008.00448.x

Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis

Beklen A., Hukkanen M., Richardson R., Konttinen Y. T.

ORAL MICROBIOLOGY AND IMMUNOLOGY, cilt.23, sa.5, ss.425-431, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 5
Basım Tarihi: 2008
Doi Numarası: 10.1111/j.1399-302x.2008.00448.x
Dergi Adı: ORAL MICROBIOLOGY AND IMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.425-431
Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background/aim: In periodontitis, bacteria and pathogen-associated molecular patterns are sensed by Toll-like receptors (TLRs), which initiate intracellular signaling cascades that may lead to host inflammation. In this study, the expression and distribution of TLRs (TLR-1 to TLR-10) were immunohistochemically detected in gingival epithelium and connective tissue.