Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis


Beklen A. , Hukkanen M., Richardson R., Konttinen Y. T.

ORAL MICROBIOLOGY AND IMMUNOLOGY, vol.23, no.5, pp.425-431, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1399-302x.2008.00448.x
  • Title of Journal : ORAL MICROBIOLOGY AND IMMUNOLOGY
  • Page Numbers: pp.425-431

Abstract

Background/aim: In periodontitis, bacteria and pathogen-associated molecular patterns are sensed by Toll-like receptors (TLRs), which initiate intracellular signaling cascades that may lead to host inflammation. In this study, the expression and distribution of TLRs (TLR-1 to TLR-10) were immunohistochemically detected in gingival epithelium and connective tissue.