Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis

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Beklen A., Hukkanen M., Richardson R., Konttinen Y. T.

ORAL MICROBIOLOGY AND IMMUNOLOGY, vol.23, no.5, pp.425-431, 2008 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 23 Issue: 5
• Publication Date: 2008
• Doi Number: 10.1111/j.1399-302x.2008.00448.x
• Journal Name: ORAL MICROBIOLOGY AND IMMUNOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.425-431
• Eskisehir Osmangazi University Affiliated: No

Abstract

Background/aim: In periodontitis, bacteria and pathogen-associated molecular patterns are sensed by Toll-like receptors (TLRs), which initiate intracellular signaling cascades that may lead to host inflammation. In this study, the expression and distribution of TLRs (TLR-1 to TLR-10) were immunohistochemically detected in gingival epithelium and connective tissue.