Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis

Beklen A., Hukkanen M., Richardson R., Konttinen Y. T.

ORAL MICROBIOLOGY AND IMMUNOLOGY, vol.23, no.5, pp.425-431, 2008 (SCI-Expanded) identifier identifier identifier


Background/aim: In periodontitis, bacteria and pathogen-associated molecular patterns are sensed by Toll-like receptors (TLRs), which initiate intracellular signaling cascades that may lead to host inflammation. In this study, the expression and distribution of TLRs (TLR-1 to TLR-10) were immunohistochemically detected in gingival epithelium and connective tissue.