Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy

ŞAHİN G., Akay O. M., USLU S., BAL C., YALÇIN A. U., Gulbas Z.

NEPHROLOGY, vol.20, no.6, pp.392-398, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1111/nep.12413
  • Journal Name: NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.392-398
  • Keywords: Adiponectin, asymmetric dimethyl arginine, cyclosporine, platelet aggregation, renal transplantation, soluble P selectin, tacrolimus, SUCCESSFUL KIDNEY-TRANSPLANTATION, P-SELECTIN LEVELS, ASYMMETRIC DIMETHYLARGININE, CARDIOVASCULAR-DISEASE, PLASMA ADIPONECTIN, CALCINEURIN INHIBITORS, DYSFUNCTION, ACTIVATION, RISK, HYPOADIPONECTINEMIA
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

AimCoagulation abnormalities, endothelial dysfunction and arteriosclerosis play a key role in cardiovascular disease state observed in transplanted patients. Plasma adiponectin levels are lower following kidney transplantation. However, there is still a debate about this topic in the literature. This study evaluated, adiponectin levels associated with markers of endothelial dysfunction and platelet function in renal transplant patients.