Evaluation of hypercoagulability state in perinatal arterial ischemic stroke with rotation thromboelastometry

Kocak O., YARAR C., Turhan A. B., Akay O. M., ÇARMAN K. B., Yakut A.

CHILDS NERVOUS SYSTEM, vol.32, no.12, pp.2395-2401, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 12
  • Publication Date: 2016
  • Doi Number: 10.1007/s00381-016-3213-0
  • Journal Name: CHILDS NERVOUS SYSTEM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2395-2401
  • Keywords: Perinatal stroke, Stroke, Prothrombotic, Thromboelastometry, RISK-FACTORS, THROMBELASTOGRAPHY, CHILDREN, THROMBOSIS, NEWBORNS, OUTCOMES, INFANTS, DISEASE
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Perinatal arterial ischemic stroke (PAIS) is an important cause of pediatric morbidity and mortality. The etiology of PAIS remains unknown. Several maternal-neonatal disorders, and especially prothrombotic risk factors, have been reported in infants with perinatal stroke (PS). Rotation thromboelastometry (ROTEM) can analyze the coagulation system, from the beginning of coagulation, through clot formation, and ending with fibrinolysis. The aim of this study was to evaluate the hypercoagulability state in PAIS patients using ROTEM.