Epithelioid angiomyolipoma of the kidney

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Acikalin M. F., Tel N., Oner U., Pasaoglu O., Donmez T.

INTERNATIONAL JOURNAL OF UROLOGY, cilt.12, sa.2, ss.204-207, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1442-2042.2005.01003.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.204-207
  • Anahtar Kelimeler: epithelioid cells, immunohistochemistry, renal tumor, RENAL ANGIOMYOLIPOMA, CELL, CARCINOMA
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, which is characterized by the presence of polygonal cells with densely eosinophilic cytoplasm and varying degrees of nuclear atypia. Only a relatively small number of cases of epithelioid angiomyolipoma of the kidney have been reported in the literature. We report a case of epithelioid angiomyolipoma of the kidney that occurred in a 38-year-old woman. The tumor was composed of diffuse sheets of epithelioid cells, adipocytes and only scattered thick-walled blood vessels. The epithelioid cells had pleomorphic and hyperchromatic nuclei with densely eosinophilic cytoplasm. Hemorrhage, necrotic foci and clusters of foamy macrophages were present. HMB-45, CD117 (c-kit) and CD68 were detected in the epithelioid cells. There was no expression of cytokeratin, epithelial membrane antigen or desmin. The patient showed no evidence of recurrence or metastatic disease 9 months after nephrectomy.