Several Cytokines and Protein C Levels with the Apache II Scoring System for Evaluation of Patients with Sepsis

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Doyuk Kartal E., Karkac E., Gulbas Z., Nayman Alpat S., Erben N., Çolak E.

BALKAN MEDICAL JOURNAL, vol.29, no.2, pp.174-178, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.5152/balkanmedj.2011.016
  • Journal Name: BALKAN MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.174-178
  • Keywords: Interleukin 6, Interleukin 8, Interleukin 1-beta, Tumor necrosis factor-alpha, Protein C, Sepsis, APACHE II, SEPTIC SHOCK, MORTALITY, COAGULOPATHY, COAGULATION, MEDIATORS, DISEASE, SCORES
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: We investigated whether determination IL-6, IL-8, IL-1beta and TNF-alpha at baseline, total protein C (PC) levels at time of admission and 48 hours after initiation could complement the Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system to identify patients with sepsis, severe sepsis or septic shock for clinical outcome.