The effects of iloprost and alprostadil on ischemia-reperfusion injury in preventing inflammation, tissue degeneration, and apoptosis in rat skeletal muscle

Guneysu E., Kocman A. E., Ozatik O., OVALI C., CAN B., ALATAŞ İ. Ö., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.3, ss.1028-1036, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1604-59
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1028-1036
  • Anahtar Kelimeler: Ischemia, reperfusion injury, iloprost, alprostadil, skeletal, muscle, PROSTAGLANDIN E-1, ISCHEMIA/REPERFUSION INJURY, LIMB, ADHESION, SURGERY, MODEL
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background/aim: The protective effects of prostaglandin (PG) analogs on ischemia-reperfusion (I/R) have been well documented; however, comparative studies are lacking. The aim of the present study was to determine whether iloprost or alprostadil is more effective in preventing muscle I/R injury.