Hepatotoxicity and nephrotoxicity following long-term prenatal exposure of paracetamol in the neonatal rat: is betaine protective?
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, sa.1, ss.99-107, 2020 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 1
- Basım Tarihi: 2020
- Doi Numarası: 10.1515/tjb-2018-0307
- Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.99-107
- Anahtar Kelimeler: Paracetamol, Pregnancy, Paraoxonase, Arylesterase, Betaine, OXIDATIVE STRESS, ACETAMINOPHEN, PARAOXONASE, INHIBITION, ACETATE, INJURY, SERUM, MODEL
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Background: Paracetamol is one of the widely used antipyretic and analgesic drug around the world. Many researchers showed that paracetamol caused to hepato-toxicity or nephrotoxicity.