Akademik Veri Yönetim Sistemi
Jinekoloji ve Obstetri Bulteni, cilt.6, sa.3, ss.99-105, 1997 (Scopus)
Objective: To define the uterine artery Doppler blood flow velocity index values in patients with endometrial carcinoma and to compare these values to those obtained from normal women. Study Design: Bilateral uterine artery Doppler blood flow velocity indexes were measured during the preoperative period in 16 cases, who were histopathologically diagnosed to have endometrial carcinoma (the study group), and in 16 normal women, who had no uterine pathology (the control group). Mean uterine artery Doppler index of each case was calculated from the right and left uterine artery Doppler indexes of that case. The mean uterine artery indexes of the study and the control groups were compared by student t test. The relations between the right and left uterine artery index values of the study group and between the uterine artery index values and the surgical stage, depth of myometrial invasion and histopathologic grade of endometrial carcinomas were evaluated by paired t test, Mann-Whitney U test and correlation analysis. Results: While any significant differences were not obtained between the right and left uterine artery Doppler index values of the 16 cases in the study group, significant correlations were observed between them with correlation coefficients of 0.77, 0.79 and 0.80 for systole/diastole (S/D) ratio, resistance index (RI) and pulsatility index (PI), respectively (p < 0.001). However, the mean uterine artery index values of the study group were significantly lower than those of the control group (p < 0.001). Meanwhile a significant negative correlation was seen between the uterine artery S/D rates and surgical stages of endometrial carcinomas with a correlation coefficient of 0.51 (p < 0.05) and the median uterine artery S/D rate of the stage III cases (2.58) was significantly lower than those of stage I (2.93) and stage II (3.75) cases (p < 0.05). Conclusion: It was suggested that uterine artery Doppler blood flow velocity indexes might be useful for early diagnoses and preoperative assessment of endometrial carcinoma.