Turkish Journal of Gastroenterology, cilt.9, sa.3, ss.284-287, 1998 (SCI-Expanded)
Colorectal carcinoma ranks as the third most common cancer seen in Turkey. The stage of cancer at diagnosis is the most important factor affecting prognosis. We have retrospectively studied 132 colorectal cases between 1993-1997. Of the 132 patients (mean age 58±6 year), 52 (39%) were female and 80 (61%) were male. No predisposing factor to colorectal carcinoma was found. The most common symptoms were abdominal pain, rectal bleeding and changes of bowel movement. Seven patients (5%) were admitted with ileus condition. The duration of their symptoms ranged between 1-24 months (mean 6±4 months). In 87 patients, the tumour was located at the rectosigmoid, in 23 the left colon, in 3 the transverse colon, in 15 the ceacum and in three at the anal canal (66%, 18%, 2%, 12%, 2%, respectively). Also, one carcinoma was discovered at appendix. Based on Duke's classification two patients were at the stage A, 22 at stage B, 55 at stage C and 52 at stage D (2%, 17%, 42%, 39%, respectively). Histopathological study revealed 124 adenocarcinomas, 3 squamos cell carcinoma, and five undifferentiated carcinomas (94%, 2%, 4%, respectively). Our findings, based on sex, age, symptoms, localisation and histologic type correlates with literature. Although it is one of the most important factors affecting prognosis, 39% of patients were at an inoperable stage. On diagnosis based on this fact, it is highly recommended that patients aged 50 and above be periodically screened for colorectal cancer.