Type IV collagen alpha-chain composition in synovial lining from trauma patients and patients with rheumatoid arthritis

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Poduval P., Sillat T., Beklen A., Kouri V. P., Virtanen I., Konttinen Y. T.

ARTHRITIS AND RHEUMATISM, cilt.56, sa.12, ss.3959-3967, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 12
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/art.23072
  • Dergi Adı: ARTHRITIS AND RHEUMATISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3959-3967
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objective. Normal synovial lining is composed of macrophage-like type A and fibroblast-like type B lining cells. This sheet-like structure lacks a basement membrane, but its intercellular substance contains some basement membrane components, including type IV collagen. We undertook this study to determine the a-chain composition of type IV collagen in normal and arthritic synovial lining, using monoclonal a-chain antibodies.