Understanding how the complex molecular architecture of mannan-degrading hydrolases contributes to plant cell wall degradation

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Zhang X., Rogowski A., Zhao L., Hahn M. G., Avci U., Knox J. P., ...More

Journal of Biological Chemistry, vol.289, no.4, pp.2002-2012, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 289 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.1074/jbc.m113.527770
  • Journal Name: Journal of Biological Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2002-2012
  • Eskisehir Osmangazi University Affiliated: No


Background: The molecular architectures of cell wall degrading enzymes are complex. Results: The activity of mannanases and esterases and CBM function against cell walls are driven by substrate context. Conclusion: GH26 and GH5 mannanases target soluble and cell wall mannans, respectively, and CBM potentiation is cell wall-dependent. Significance: The context of cell wall polysaccharides drives the molecular architectures of cell wall-degrading enzymes. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.