Synthesis of Some New Thiazole Derivatives and Their Biological Activity Evaluation

YURTTAŞ, LEYLA; ÖZKAY, YUSUF; KARACA GENÇER, HÜLYA; Acar, Ulviye

doi:10.1155/2015/464379

Synthesis of Some New Thiazole Derivatives and Their Biological Activity Evaluation

YURTTAŞ L., ÖZKAY Y., KARACA GENÇER H., Acar U.

JOURNAL OF CHEMISTRY, vol.2015, 2015 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 2015
Publication Date: 2015
Doi Number: 10.1155/2015/464379
Title of Journal : JOURNAL OF CHEMISTRY

Abstract

New 2-(4-arylpiperazine-1-yl)-N-[4-(2-(4-substituted phenyl)thiazol-4-yl)phenyl]acetamide derivatives were synthesized and evaluated for their antimicrobial and anticholinesterase activities. Acetylcholinesterase inhibitory activities of the compounds were found weak contrary to expectations. It is unlikely that antifungal activity of the compounds was found significant, especially against Candida parapsilosis.