© 2019 Turkish Society of Cardiovascular Surgery.A 54-year-old male patient admitted to our hospital with rightsided chest pain. Chest X-ray revealed a large expansive lesion arising from the eighth rib. On his computed tomography, paravertebral localized well-defined expansive lytic 4 × 3 cm diameter mass was described. Wide en bloc excision of seventh and eighth rib was performed. In this article, we report a case of intraosseous lipoma involved in the eighth rib under the review of the literature.