Antimicrobial Activities of Propolis Samples Collected From Different Provinces of Turkey

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Gülbandılar A.

MAS Journal of Applied Sciences, vol.7, no.2, pp.433-442, 2022 (Peer-Reviewed Journal)


he propolis, which is a natural product that is collected by honey bees from the plants, especially 

flowers and buds, by mixing it with wax and resin, is used in the hive for many purposes. Apart from the 

use by the bees in the hive, propolis is a versatile compound that is used in medicine, cosmetics, food 

industry and apitherapy and which contains a wide variety of chemical substances having antibacterial and 

antioxidant effects. It was determined that the antimicrobial effects of propolis samples were higher against 

the Gram-positive bacteria species included in the study when compared to the Gram-negative bacteria and 

yeasts. The majority of the samples were found to be highly sensitive (16 mm and larger), while some were 

found to be moderately sensitive (11-15 mm). Among all strains of bacteria; it was demonstrated that the 

propolis sample obtained from Cankiri (Yaprakli) region performed the highest activity against 

Staphylococcus aureus while the lowest activity was performed by the propolis sample obtained from 

Balıkesir region against E. coli. In addition, it was determined that the propolis sample obtained from 

Eskişehir region had no antifungal effect against Candida parapsilosis yeast strain. It was specified that the 

antimicrobial activity demonstrated by all microorganisms against the propolis samples was less effective 

when compared to the control compounds, except for Candida krusei.