MAS Journal of Applied Sciences, cilt.7, sa.2, ss.433-442, 2022 (Hakemli Dergi)
he propolis, which is a natural product that is collected by honey bees from the plants, especially
flowers and buds, by mixing it with wax and resin, is used in the hive for many purposes. Apart from the
use by the bees in the hive, propolis is a versatile compound that is used in medicine, cosmetics, food
industry and apitherapy and which contains a wide variety of chemical substances having antibacterial and
antioxidant effects. It was determined that the antimicrobial effects of propolis samples were higher against
the Gram-positive bacteria species included in the study when compared to the Gram-negative bacteria and
yeasts. The majority of the samples were found to be highly sensitive (16 mm and larger), while some were
found to be moderately sensitive (11-15 mm). Among all strains of bacteria; it was demonstrated that the
propolis sample obtained from Cankiri (Yaprakli) region performed the highest activity against
Staphylococcus aureus while the lowest activity was performed by the propolis sample obtained from
Balıkesir region against E. coli. In addition, it was determined that the propolis sample obtained from
Eskişehir region had no antifungal effect against Candida parapsilosis yeast strain. It was specified that the
antimicrobial activity demonstrated by all microorganisms against the propolis samples was less effective
when compared to the control compounds, except for Candida krusei.