EVALUATION OF GREENNESS PROFILES OF VARIOUS DEVELOPED METHODS FOR THE DETERMINATION OF COMMONLY USED NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) IN ENVIRONMENTAL WATERS


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sezgin b., Soyseven M.

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, cilt.48, sa.2, ss.535-543, 2024 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.33483/jfpau.1425350
  • Dergi Adı: Ankara Üniversitesi Eczacılık Fakültesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.535-543
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: In our study, it was aimed to make a comparative analysis of the environmental impact profiles of two approaches including Gas Chromatography (GC) and Liquid Chromatography (LC) methods, which are frequently used techniques for the determination of non-steroidal anti-inflammatory drugs (NSAIDs) and their metabolites in environmental water samples. Material and Method: The evaluation of the methods' environmental impact was performed using National Environmental Methods Index Label (NEMI), Analytical Eco-scale, Analytical GREEnness Metric (AGREE), and Green Analytical Procedure Index (GAPI). Result and Discussion: The routine analysis of NSAIDs in environmental waters is carried out, resulting in a significant volume of chemical waste. In recent times, there has been a growing significance attributed to environmentally conscious analytical methodologies and the evaluation of methodologies through a green lens to confront this challenge. There is no statistically significant difference in terms of environmental impact profile was observed between the two methods compared.