Inflammation and Oxidative Stress in Deficit Schizophrenia.

KÖŞger F., YİĞİtaslan S., EŞsİzoĞlu A., GÜleÇ G., KarataŞ R. D., DeĞİrmencİ S. S.

Noro psikiyatri arsivi, vol.57, no.4, pp.303-307, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.29399/npa.24966
  • Journal Name: Noro psikiyatri arsivi
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, Psycinfo, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.303-307
  • Keywords: Deficit schizophrenia, schizophrenia, inflammation, cytokine, oxidative stress, 1 PON1 ACTIVITY, CYTOKINE ALTERATIONS, RELIABILITY, PSYCHOSIS, SCHEDULE, VALIDITY
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Introduction: Differences in parameters related to inflammatory and oxidative stress in deficit (DS) and nondeficit schizophrenia (non-DS) may support the DS/non-DS categorization of schizophrenia. For DS patients, non-DS patients, and for healthy controls, this study aims to evaluate the serum levels of: proinflammatory cytokines of interleukin (IL) 1 beta, tumor necrosis factor (TNF) alpha, Interferon (IFN)gamma, IL-12, and IL-17; anti-inflammatory cytokines of IL-10, IFN-alpha, and transforming growth factor (TGF) beta; and antioxidant biomarkers of paraoxonase1 (PON1) and Total Antioxidant Capacity (TAOC).