Inflammation and Oxidative Stress in Deficit Schizophrenia.
Noro psikiyatri arsivi, cilt.57, sa.4, ss.303-307, 2020 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 57 Sayı: 4
- Basım Tarihi: 2020
- Doi Numarası: 10.29399/npa.24966
- Dergi Adı: Noro psikiyatri arsivi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, Psycinfo, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.303-307
- Anahtar Kelimeler: Deficit schizophrenia, schizophrenia, inflammation, cytokine, oxidative stress, 1 PON1 ACTIVITY, CYTOKINE ALTERATIONS, RELIABILITY, PSYCHOSIS, SCHEDULE, VALIDITY
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Introduction: Differences in parameters related to inflammatory and oxidative stress in deficit (DS) and nondeficit schizophrenia (non-DS) may support the DS/non-DS categorization of schizophrenia. For DS patients, non-DS patients, and for healthy controls, this study aims to evaluate the serum levels of: proinflammatory cytokines of interleukin (IL) 1 beta, tumor necrosis factor (TNF) alpha, Interferon (IFN)gamma, IL-12, and IL-17; anti-inflammatory cytokines of IL-10, IFN-alpha, and transforming growth factor (TGF) beta; and antioxidant biomarkers of paraoxonase1 (PON1) and Total Antioxidant Capacity (TAOC).