EUROPEAN JOURNAL OF ANAESTHESIOLOGY, cilt.21, sa.3, ss.205-209, 2004 (SCI-Expanded)
Background and objective: Clonidine has cardiac and systemic effects that can modify the potentially lethal cardiovascular effects of local anaesthetics. We evaluated the effects of clonidine pre-treatment on cardiotoxicity induced by an infusion of bupivacaine or ropivacaine and the success rate of resuscitation in anaesthetized rats.