High serum bilirubin concentrations preserve coronary flow reserve and coronary microvascular functions

Gullu H., Erdogan D., Tok D., Topcu S., Caliskan M., Ulus T., ...More

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, vol.25, no.11, pp.2289-2294, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 11
  • Publication Date: 2005
  • Doi Number: 10.1161/01.atv.0000185806.61430.7c
  • Journal Name: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2289-2294
  • Keywords: coronary flow reserve, bilirubin, echocardiography, ALBUMIN-BOUND BILIRUBIN, LOW-DENSITY-LIPOPROTEIN, 2ND-HARMONIC ECHO-DOPPLER, ISCHEMIC-HEART-DISEASE, LEFT-VENTRICULAR MASS, ARTERY-DISEASE, LIPID-PEROXIDATION, ANTIOXIDANT ACTIVITY, HEME OXYGENASE, RISK
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background-Elevated serum bilirubin concentrations protect against atherosclerotic diseases; however, it is not clear whether higher serum bilirubin concentrations in physiological ranges work in favor of the cardiovascular system in younger persons with no cardiovascular risk factors. Accordingly, we investigated the effects of high, intermediate, and low serum bilirubin concentrations on coronary flow reserve (CFR).