Neutrophil Gelatinase-Associated Lipocalin: A New Biomarker for the Differential Diagnosis of Anemia?


Temiz G., Akay M., Karagulle M., Tokmak S., MUTLU F. , YALÇIN A. U.

TURKISH JOURNAL OF NEPHROLOGY, vol.28, no.1, pp.48-53, 2019 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5152/turkjnephrol.2019.2934
  • Title of Journal : TURKISH JOURNAL OF NEPHROLOGY
  • Page Numbers: pp.48-53

Abstract

Objective: Differential diagnosis of iron deficiency anemia (IDA) and anemia of chronic disease (ACD) is performed based on some biochemical indicators of iron metabolism. Although these traditional indicators are useful to determine iron status, they may not provide conclusive criteria for determining iron deficiency because of their high variability and low sensitivity. The aim of the present study was to evaluate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) in the differential diagnosis of IDA and ACD and to compare it with other conventional anemia parameters.