Neutrophil Gelatinase-Associated Lipocalin: A New Biomarker for the Differential Diagnosis of Anemia?

Temiz G., Akay M., Karagulle M., Tokmak S., MUTLU F., YALÇIN A. U.

TURKISH JOURNAL OF NEPHROLOGY, cilt.28, sa.1, ss.48-53, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/turkjnephrol.2019.2934
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.48-53
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Differential diagnosis of iron deficiency anemia (IDA) and anemia of chronic disease (ACD) is performed based on some biochemical indicators of iron metabolism. Although these traditional indicators are useful to determine iron status, they may not provide conclusive criteria for determining iron deficiency because of their high variability and low sensitivity. The aim of the present study was to evaluate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) in the differential diagnosis of IDA and ACD and to compare it with other conventional anemia parameters.