JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, vol.62, 2020 (Peer-Reviewed Journal)
Article / Article
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
Science Citation Index Expanded, Scopus, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
Cyclophosphamide, Testicular damage, Apoptosis, Boron, Anti-Oxidant, Lipid per oxidation, GERM-CELL APOPTOSIS, BORIC-ACID, DIETARY BORON, ELLAGIC ACID, DAMAGE, TOXICITY, GENOTOXICITY, METABOLITES, EXPOSURE, BLOOD
Background: Cyclophosphamide (CP) is an alkylating chemotherapeutic drug used in the treatment of many types of cancer. However, as with other chemotherapeutic drugs, the use of CP is limited by the damage to healthy tissues such as testes, bladder and liver as well as cancerous tissue. Boron (B) is a trace element with many biological properties such as antioxidant, anti-apoptotic and anti-lipid per oxidation.