Serum Thrombopoietin Levels and Its Relationship With Thrombocytopenia in Patients With Cirrhosis

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TEMEL T., ÜSKÜDAR CANSU D., TEMEL H. E., ÖZAKYOL A.

HEPATITIS MONTHLY, vol.14, no.5, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 14 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.5812/hepatmon.18556
  • Journal Name: HEPATITIS MONTHLY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Liver Cirrhosis, Thrombocytopenia, Thrombopoietin, CHRONIC LIVER-DISEASE, CHRONIC HEPATITIS, INFECTION, TRANSPLANTATION
  • Open Archive Collection: AVESIS Open Access Collection
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: Patients with cirrhosis usually have thrombocytopenia in discrete levels. The mechanism of thrombocytopenia is thought as splenic sequestration and destruction of platelets, impaired bone marrow generation and diminished hepatic thrombopoietin synthesis.