The aim of this study is to define and compare sexual dysfunctions of women with and without infertility problems. This descriptive and comparative study was conducted between February 2014 and February 2016. The population of the study were women with and without infertility problems that applying to infertility and gynecology outpatient clinics of Ataturk University Research Hospital in Erzurum city center of Turkey. 137 women with infertility problems and 142 women without infertility problems were included in the study. Questionnaire and Female Sexual Function Index (FSFI) were used to collect the data of the study. It was determined that while total mean score of FSFI of the women without infertility problems was 17.86 +/- 6.41, FSFI of the women with infertility problems was 17.49 +/- 7.20. The difference between FSFI sub-scale and total mean score of women with and without infertility problems was not statistically significant. When it was evaluated in terms of cut-off point of FSFI, it was found that except for subscale of Satisfaction among its subscales, difference between all other subscales was not statistically significant (p > 0.05). It was found that 76.8% of the women without infertility problems and 78.8% of the women with infertility problems had sexual dysfunctions and the difference between the groups was not statistically significant (p > 0.05). As a result of FSFI scores of the women with and without infertility problems, it was concluded that both groups had sexual dysfunctions and there was no statistically significant difference between them.