The In Vivo Antinociceptive and Antiinflammatory Effects of Verbascum exuberans Hub.-Mor.

Eyiiş E., Kaygısız B., Kılıç F. S., Ayhancı A.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.17, no.6, pp.586-592, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.4274/tjps.galenos.2019.77992
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.586-592
  • Keywords: Verbascum exuberans Hub.-Mor., Scrophulariaceae, antinociceptive effect, antiinflammatory effect, tramadol, NITRIC-OXIDE, MEDICINAL-PLANTS, COMMON MULLEIN, RECEPTOR, PAIN, MECHANISM, TRAMADOL, EDEMA, PAW, L.
  • Eskisehir Osmangazi University Affiliated: Yes


Objectives: Safe and effective drugs are still lacking for many pain therapies. In recent years, growing interest has been devoted thus on herbal drugs as an option to identify new pain killers. Based on this, extensive researches are carried out on Verbascum L. genus due to its therapeutic potency on pain and inflammation therapy. In this study, among Verbascum species, the antinociceptive effect of Verbascum exuberans Hub.-Mor., and its contributions to nitrergic, serotonergic, or opioidergic pathways as well as its antiinflammatory acitivity were investigated.