Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines

Oturanel C. E., KIRAN İ., ÖZŞEN BATUR Ö., AKALIN ÇİFTÇİ G., ATLI Ö.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, sa.9, ss.1243-1250, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1871520617666170103093923
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1243-1250
  • Anahtar Kelimeler: Anticancer, antiproliferative, apoptosis, biotransformation, cytotoxicity, perillyl alcohol, BIOLOGICAL EVALUATION, DERIVATIVES, ANTICANCER, MONOTERPENES, PREVENTION, EXPRESSION, DRUGS, ACID
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers.