Clostridium difficile Colitis Prevention and Treatment

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Atıf İçin Kopyala

DİNLEYİCİ M., Vandenplas Y.

PROBIOTICS AND CHILD GASTROINTESTINAL HEALTH: ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH, VOL 10, cilt.1125, ss.139-146, 2019 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 1125
• Basım Tarihi: 2019
• Doi Numarası: 10.1007/5584_2018_322
• Dergi Adı: PROBIOTICS AND CHILD GASTROINTESTINAL HEALTH: ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH, VOL 10
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
• Sayfa Sayıları: ss.139-146
• Anahtar Kelimeler: Antibiotic associated diarrhea, Clostridium difficile, Colitis, ANTIBIOTIC-ASSOCIATED DIARRHEA, FECAL MICROBIOTA TRANSPLANTATION, SACCHAROMYCES-BOULARDII, RISK-FACTORS, INFECTION, PROBIOTICS, CHILDREN, VANCOMYCIN, DISEASE, ADULTS
• Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Clostridium difficile (C. diff) is the most common causative agent of antibiotic-associated diarrhea and colitis. This spore-forming, obligate anaerobic, gram-positive bacillus is becoming responsible for an increasing number of infections worldwide, both in community and in hospital settings, whose severity can vary widely from an asymptomatic infection to a lethal disease. While discontinuation of antimicrobial agents and antibiotic treatment of the infection remain the cornerstone of therapy, the use of probiotics, especially Saccharomyces boulardii, and more recently of fecal microbiota transplantation have become valid forms of prevention and/or therapy and are here critically examined.